Plant sterols are natural active substances, which can lower the total cholesterol content in serum and low-density lipoprotein cholesterol levels. They have a wide range of uses in food, cosmetics, medicine and other fields, and have very good market prospects. However, the water insolubility of phytosterols limits its use in the food industry.
Hydroxypropyl beta-cyclodextrin is an excellent pharmaceutical excipient. It is not only water-soluble, but also non-toxic and harmless. It is a very good inclusion material for alkali, light and heat. The hydroxypropyl beta-cyclodextrin is used to encapsulate the plant sterol, and the non-polar cavity provides a good encapsulation space for the non-polar carbon chain portion of the sterol, and then the hydroxy group portion of the sterol itself is exposed at the outer end, and The hydroxyl groups possessed by the cyclodextrin themselves add to the overall hydrophilic character, thereby improving the solubility of the sterol in water. |